man that beat goes hard (especially the muted kit from 2:15-2:39); love how it compliments the 7/4! I appreciate odd time sigs that don't actually feel especially odd, and this is definitely that; not to mention that this just sounds clean as hell as a whole. I can only think of two suggestions:
I think the ending chord can be stretched a bit longer to make it sound more definitive as a finisher (if this is intended as a loop, ignore this entire sentence); as it stands, that chord progression is awesome and beautiful, and it feels like it stops a bit too abruptly for how beautiful it is; I think you could milk that feeling for juust a bit longer.
I'd also recommend a little more dynamic/velocity variation, specifically in individual lines/instruments. Now, when it gets big, and there's a lot of moving parts anyway (mostly talking about 1:11-1:50), while it would still be pretty neat, it's not as important. But at other points, especially when it's more melodic, I think having a line (or drum pattern) get louder and quieter, emphasizing and de-emphasizing, would create a really nice flow that you usually only hear in songs using acoustic instruments. While I already really like the pretty melodies (that keyboard stuff holy moly, and that screaming and sliding synth at 1:11-1:50 too) and the full-sounding chords, I think dynamic variation could really make everything come alive.
Overall this is really cool, and yeah the Risk of Rain comes through loud and clear lol (love that soundtrack). Oh, and 7's (5's too) need to be normalized across the board; they're too cool sounding